Insilico Identification of Potent Inhibitor from Andrographis Paniculata for ESBLs

Andrographis paniculata (Burm.f) Wall. ex Ness: A Potent Antibacterial Plant

Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)

Andrographis paniculata (Burm. f.) Nees (Acanthaceae) is a medicinal plant used in many countries. Its major constituents are diterpenoids, flavonoids and polyphenols. Among the single compounds extracted from A. paniculata, andrographolide is the major one in terms of bioactive properties and abundance. Among the andrographolide analogues, 14-deoxy-11,12-didehydroandrographolide is immunostimu...

Hepatoprotective Diterpenoids Isolated from Andrographis paniculata

Andrographis paniculata (Burm.f.) Nees (Acanthaceae), a plant widely used as traditional herbal medicine in many countries, has drawn attention of the researchers in recent years. Its major constituents are diterpenoids and flavonoids. This article reviews the anti-hepatotoxic effects of A. paniculata extract and derivative compounds, such as andrographolide, the major active compound, most stu...

Andrographolide isolated from Andrographis paniculata Ness

Andrographolide isolated from Andrographis paniculata Ness (A and 1.40 mM induced DNA fragmentation and increased the percentage o breast cancer cell line was treated for 24 , 48 and 72 h. The results de induce apoptosis in TD-47 human breast cancer cell line in a time and increase expression of p53, bax , caspase-3 and decrease ex immunohistochemical analysis.

Bisandrographolide from Andrographis paniculata activates TRPV4 channels.

Many transient receptor potential (TRP) channels are activated or blocked by various compounds found in plants; two prominent examples include the activation of TRPV1 channels by capsaicin and the activation of TRPM8 channels by menthol. We sought to identify additional plant compounds that are active on other types of TRP channels. We screened a library of extracts from 50 Chinese herbal plant...